Altomare CG, Adelsberg DC, Carreno JM, Sapse IA, Amanat F, Ellebedy AH, Simon V, Krammer F, Bajic G. Structure of a germline-like human antibody defines a neutralizing epitope on the SARS-CoV-2 spike NTD. bioRxiv 2021.07.08.451649; doi: https://doi.org/10.1101/2021.07.08.451649

Feldman J, Bals J, Altomare CG, St. Denis K, Lam EC, Hauser BM, Ronsard L, Sangesland M, Moreno TB, Okonkwo V, Hartojo N, Balazs AB, Bajic G, Lingwood D, Schmidt AG. Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses. 2021 Science Immunology, doi:10.1126/sciimmunol.abl5842

Aaron J. Schmitz, Jackson S. Turner, Zhuoming Liu, Ishmael D. Aziati, Rita E. Chen, Astha Joshi, Traci L. Bricker, Tamarand L. Darling, Daniel C. Adelsberg, Clara G. Altomare, Wafaa B. Alsoussi, James Brett Case, Tingting Lei, Mahima Thapa, Fatima Amanat, Jane A. O’Halloran, Pei-Yong Shi, Rachel M. Presti, Florian Krammer, Sean P.J. Whelan, Goran Bajic, Michael S. Diamond, Adrianus C. M. Boon, Ali H. Ellebedy. A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants. 2021 Immunity, DOI:https://doi.org/10.1016/j.immuni.2021.08.013

Amanat F, Thapa M, Lei T, Ahmed SMS, Adelsberg DC, Carreno JM, Strohmeier S, Schmitz AJ, Zafar S, Zhou JQ, Rijnink W, Alshammary H, Borcherding N, Reiche AG, Srivastava K, Sordillo EM, van Bakel H; Personalized Virology Initiative, Turner JS, Bajic G*, Simon V*, Ellebedy AH*, Krammer F*. SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD and S2. 2021 Cell, doi: https://doi.org/10.1016/j.cell.2021.06.005.

* corresponding

 

Tong P, Gautam A, Windsor I, Travers M, Chen Y, Garcia N, Whiteman NB, McKay LGA, Lelis FJN, Habibi S, Cai Y, Rennick LJ, Duprex WP, McCarthy KR, Lavine CL, Zuo T, Lin J, Zuiani A, Feldman J, MacDonald EA, Hauser BM, Griffths A, Seaman MS, Schmidt AG, Chen B, Neuberg D, Bajic G, Harrison SC, Wesemann DR. Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike. 2021 Cell Jul 23:S0092-8674(21)00884-9. doi: 10.1016/j.cell.2021.07.025. PMID: 34332650

Bajic G.*, Harrison SC. Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses. 2020 ACS Infect Dis. doi: 10.1021/acsinfecdis.0c00726

* corresponding

Bajic G., Maron M.J., Caradonna T.M., Tian M., Mermelstein A., Fera D., Kelsoe G., Kuraoka M. and Schmidt A.G. Structure-Guided Molecular Grafting of a Complex Broadly Neutralizing Viral Epitope. 2020 ACS Infect Dis. 6(5), 1182-1191. doi:10.1021/acsinfecdis.0c00008 

van der Poel C.E., Bajic G., Macaulay C.W., Ellson C.D., Bouma G., Victora G.D., Degn S.E. and Carroll M.C. Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB. 2019 Cell Reports 29, 2745-2755

Bajic G., Maron, M. J., Adachi, Y., Onodera, T., McCarthy, K. R., McGee, C. E., Sempowski, G. D., Takahashi, Y., Kelsoe, G., Kuraoka, M. and Schmidt, A. G. Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope. 2019 Cell Host Microbe 25, 827-835

Watanabe, A., McCarthy, K. R., Kuraoka, M., Schmidt, A. G., Adachi, Y., Onodera, T., Tonouchi, K., Caradonna, T. M., Bajic, G., Song, S., McGee, C. E., Sempowski, G. D., Feng, F., Urick, P., Kepler, T. B., Takahashi, Y., Harrison, S. C., and Kelsoe, G. Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. 2019 Cell 177, 1124-1135

Bajic G., van der Poel C.E., Kuraoka M., Schmidt A.G., Carroll M.C., Kelsoe G. and Harrison S.C. Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies. 2019 Sci Rep. 9(1):3492. doi: 10.1038/s41598-019-40175-8

Raymond D.D.*, Bajic G.*, Ferdman J., Suphaphiphat P., Settembre E.C., Moody M.A., Schmidt A.G., Harrison S.C. Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody. 2018 Proc Natl Acad Sci U S A. 115(1):168-173 doi: 10.1073/pnas.1715471115.
* co-first author

Degn S.E., van der Poel C.E., Firl D.J., Ayoglu B., Al Qureshah F.A., Bajic G., Mesin L., Reynaud C.A., Weill J.C., Utz P.J., Victora G.D., Carroll M.C. Clonal evolution of autoreactive germinal centers. 2017 Cell. 170(5):913-926

Raymond D., Stewart S., Lee J., Ferdman J., Bajic G., et al. and Harrison S.C. Influenza immunization elicits hemagglutinin receptor-site antibodies specific for an egg-adapted vaccine strain. 2016 Nature Medicine 22(12):1465-1469

Jensen R.M.*, Bajic G.*, Zhang X.*, Laustsen A.K., Koldso H., Kirkeby Skeby K., Schiott B., Andersen G.R., and Vorup-Jensen T. Structural basis for simvastatin competitive antagonism of complement receptor 3. 2016 J. Biol. Chem 291(33):16963-76
* co-first author

Zhang X., Bajic G., Andersen G.R., Christiansen S.H. and Vorup-Jensen T. The cationic peptide LL-37 binds Mac-1 (CD11b/CD18) with a low dissociation rate and promotes phagocytosis. 2016 Biochim. Biophys. Acta 1864: 471–8

Bajic G., Degn S.E., Thiel S. and Andersen G.R. Complement activation, regulation and molecular basis for complement-related diseases. 2015 EMBO J. 34: 2735–57

Yatime L., Bajic G., Schatz-Jakobsen J.A. and Andersen G.R. Complement regulators and inhibitors in health and disease: A structural perspective. 2016 Nanomedicine, CRS Advances in Delivery Science and Technology Book Series.

Bajic G., Yatime L., Sim R.B., Vorup-Jensen T. and Andersen G.R. Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3. Proc Natl Acad Sci U S A 2013 110(41) ; 16426-31

Bajic G., Yatime L., Klos A. and Andersen G.R. Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg. Protein Science, 2013 22(2): 204-212.

Stelter M., Gutsche I., Kapp U., Bazin A., Bajic G., Goret G., Jamin M., Timmins J. and Terradot L. Architecture of a dodecameric bacterial replicative helicase. Structure. 2012 20(3) : 554-64

Rhimi M., Bajic G., Ilhammami R., Boudebouze S., Maguin E., Haser R., and Aghajari N.
The relevant L-arabinose isomerase from Shewanella sp. ANA-3 is highly active at low temperatures. Microbial Cell Factories 2011 ; 10:96

Rhimi M., Ilhammami R., Bajic G., Boudebouze S., Maguin E., Haser R., and Aghajari N.
The acid tolerant L-arabinose isomerase from the food grade Lactobacillus sakei 23K is an attractive D-tagatose producer. Bioresource Technology 2010 101(23) ; 9171-7

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